Innate immunity and epigenetic plasticity in cellular reprogramming
نویسندگان
چکیده
منابع مشابه
Epigenetic Control of Reprogramming and Cellular Differentiation
1Dulbecco Telethon Institute (DTI), IRCCS Fondazione Santa Lucia and European Brain Research Institute, 00143 Rome, Italy 2National Research Council, Institute of Translational Pharmacology, via Fosso del Cavaliere 100, 00133 Rome, Italy 3 Institute of Predictive and Personalized Medicine of Cancer (IMPPC), 08916 Badalona, Spain 4 Sanford-Burnham Institute for Medical Research, La Jolla, CA 920...
متن کاملNuclear cloning, epigenetic reprogramming, and cellular differentiation.
The full-term development of sheep, cows, goats, pigs and mice has been achieved through the transfer of somatic cell nuclei into enucleated oocytes. Despite these successes, mammalian cloning remains an inefficient process, with a preponderance of reconstructed embryos failing at early- to mid-gestation stages of development. The small percentage of conceptuses that survive to term are charact...
متن کاملInnate cellular immunity and xenotransplantation.
PURPOSE OF REVIEW This review assesses the recent progress in xenograft rejection by innate immune responses, with a focus on innate cellular xenoreactivity. RECENT FINDINGS Current literature was reviewed for new insights into the role of innate cellular immunity in xenograft rejection. Increasing evidence confirms that vigorous innate immune cell activation is accounted for by a combination...
متن کاملEpigenetic Regulation of Innate Immunity by microRNAs
The innate immune response, which is usually referred to as the first line of defense, protects the hosts against pathogenic micro-organisms. Some of the biomolecules released from the pathogens, such as proteins, lipoproteins and nucleic acids, which are collectively termed as pathogen-associated molecular patterns (PAMPs), elicit signaling mechanisms that trigger immune responses in the hosts...
متن کاملGlobal Epigenetic State Network Governs Cellular Pluripotent Reprogramming and Transdifferentiation
Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24060, USA Center for Complex Network Research, Departments of Physics, Biology, and Computer Science, Northeastern University, Boston, MA 02115, USA. Department of Medicine, Harvard Medical School, and Center for Cancer Systems Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA. National Heart, Lung and Blood Institutes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Opinion in Genetics & Development
سال: 2014
ISSN: 0959-437X
DOI: 10.1016/j.gde.2014.11.002